What’s New in perimenopause


  • When Helen came to see me at 48, she’d been told her only option was more HRT — but her hot flushes, anxiety, poor sleep and brain fog were still running her life. We treated…


  • Sore, swollen breasts in early perimenopause often come down to low iodine leaving breast tissue over-reactive to oestrogen — not a shortage of oestrogen to top up with HRT.


  • Pain under your right ribs that creeps round to your back or shoulder is one of those symptoms women often dismiss as “just indigestion” or “I must have eaten too fast.” In my clinic, it’s…


  • If you constantly battle dark circles under your eyes no matter how much sleep you get or concealer you use, excess histamine could be the culprit.


  • Perimenopause has 66 recognised symptoms, but they aren’t 66 separate problems.

From my Substack

I write regularly about menopause, symptoms, biology, and the wider story women are so often not told. Some of the articles will be part of my book. If you want to go deeper into the thinking behind my work, you can start here.

The Ultimate Guide to Perimenopause and Menopause: Making Sense of the Chaos
Perimenopause and the ADHD Shift

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Not ready to book? Follow my thinking on Substack


Sandra Ishkanes  Natural Menopause Specialist based in Brighton, serving clients worldwide via Online Consultations   
BSc Molecular Biology (King’s College London) | DipION | Functional Medicine Practitioner
Registered member, Association of Naturopathic Practitioners (ANP) – the UK professional body for accredited naturopathic and functional medicine practitioners. ANP members hold accredited qualifications, carry professional indemnity insurance, and follow a strict code of ethics.

© 2026 Sandra Ishkanes  ·  sandraishkanes.co.uk

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The information provided on this website is for educational and informational purposes only and is not intended as medical advice, diagnosis, or treatment. Sandra Ishkanes is a Functional Medicine Practitioner and Molecular Biologist, not a medical doctor. Always seek the advice of your GP or other qualified healthcare provider with any questions you may have regarding a medical condition or before making any changes to your diet, lifestyle, or supplement regimen—especially if you are currently taking prescription medication or HRT. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.