Fibroids feed on oestrogen — and early perimenopause is when oestrogen runs highest and least opposed. As ovulation skips and progesterone crashes (the Progesterone Shift), oestrogen dominates, and the growth it drives is amplified by…
Sudden perimenopausal anxiety and worsening ADHD in early perimenopause are driven by a biochemical traffic jam. As progesterone drops and heavy bleeding drains iron, chaotic oestrogen spikes actively suppress the COMT enzyme, trapping adrenaline in your body.…