Pause menopause with Rhodiola rosea, a natural selective estrogen receptor modulator
Menopause is associated with increased risks for cardiovascular disease, osteoporosis, and cancer. Many women experience declining energy, mood, cognitive function and memory during
menopause.
Rhodiola rosea extracts have been shown to enhance mood, cognitive function, and memory. Moreover, these extracts possess anti-stress, neuroprotective, cardiovascular-protective, and anticarcinogenic properties, which are particularly valuable to counteract some of the common health risks seen in women as they age. R. rosea is low in side effects compared to synthetic selective estrogen receptor modulators (SERMS).
Preclinical and clinical studies suggest that R. rosea extracts provide a combination of effects that could counteract the adverse consequences of estrogen decline by improving neurological, endothelial, and cardiovascular functions.
As a natural SERM, R. rosea could alleviate menopause-related symptoms while conferring additional neuro-protective, cardio-protective, anti-stress, anti-fatigue, osteoprotective, and other health benefits.
Unlike HRT, preliminary evidence indicates that orally ingested R. rosea extracts are unlikely to cause estrogenic effects or increased the risk of cancer in hormone sensitive tissues. R. rosea extracts and salidroside do not significantly stimulate, but rather inhibit growth of human breast cancer in vitro and in vivo in some studies. Human studies are needed to verify the safety of R. rosea in postmenopausal women who are at increased risk or who are being treated for breast cancer.
Further research on the use of R. rosea alone and in combination with other adaptogens during menopause would enable development of this promising alternative SERM.
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This study looked at more than 7,000 women over 60 in the US (NHANES 2005–2020) to understand how the age at menopause relates to depression in later life,…
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3,000 women were followed for 10 years to ask a simple question: does the menopausal transition itself increase the risk of significant anxiety symptoms? What was…
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This long-term study followed 233 women from before menopause to after their final period to see how different types of anxiety relate to hot flushes.…
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This study followed 122 late peri‑ and postmenopausal women (average age 59) to see how their sleep relates to early brain changes that raise the…
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While osteoporosis and psychological stress occur via differing mechanisms, there are several potential molecular links that exist between a pathological response to stress and the…
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Excess glucocorticoids are well recognised as a cause of osteoporosis; they inhibit osteoblast function and increase osteoblast and osteocyte apoptosis resulting in thinning of the…
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Osteoporosis, a consequence of menopause in the biological cycle of women, emerges with the conclusion of reproductive capabi lities.Hormonal changes during this phase contribute to…
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The purpose of this study was to determine the longitudinal association between menopausal vasomotor symptoms (VMS) and urinary N-telopeptide level (NTX) according to menopausal stage. We…
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Objective: To determine whether women with vasomotor symptoms (VMS) have lower bone mineral density (BMD) than women without VMS. Design We analyzed data from baseline…
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